ST JOHN'S WORT

Hypericum perforatum

ACTIVE INGREDIENTS:

Some of which include Hypericin, pseudohypericin, hyperin, hyperforin, flavonoids, tannins

·          MOA inhibiting activity.  The phyto-substances responsible for this include quericitin, pseudohypericin and xanthones. Taken as a whole plant extract these substances do not pose the usual MAO inhibiting risk.

·     TCA –like activity.  In 1997 further studies revealed that Hypericum appeared also to act on the levels of norepinephrine and dopamine giving it tricyclic antidepressant characteristics.

·     SSRI- like activity may be attributed to the phtyo-chemical hypericin, xanthones and flavanoid amentoflavone.

·     Sedative effects may be attributed to hyperin, biflavone and the amino acid gamma-amino butyric acid.

 RESEARCH :

·         MOA inhibiting activity increases the level of seratonin in the brain. This accounts for feelings of contentment

·         Some active ingredients act on levels of dopamine levels in the brain. Responsible for movement and feelings of pleasure.

·         Other active ingredients have a calming effect.

·         St John’s Wort has demonstrated antiviral activity.

·         Flavonoids are anti-inflammatory.

·         Astringent constituents may be used to address blood vessel integrity

 WHAT ARE ITS USES:

·         May be regarded as a long-term treatment for depression improving a sense of contentment.

·         Raised seratonin levels may assist in cases of insomnia improving sleep patterns and quality.

·         May be used as a support while trying to quit habits like smoking, excessive alcohol consumption, over eating etc

·         May be used to stimulate the immune system and eliminate toxins from system.

·         May be used during recovery from injury.

·         Has Antiviral properties

·         May help in treating compulsive eating disorder, assisting in weight loss.

·         Found to reduce pre-menstrual and menopausal symptoms

·         Research has found St John's Wort to be helpful in treating Attention Deficit Disorder

·         External Topical use for conditions like shingles

TREATING DEPRESSION WITH ST JOHN’S WORT

It is not fully understood how Hypericum treats depression but researchers are getting closer to some conclusive answers.

It is not recommended that Major Depressive Disorders, Dysthymic Disorders, Bipolar Disorders and Cyclothymic Disorders be treated with St John’s without professional advice. In addition to this there is still insufficient conclusive research findings on St Johns Wort efficacy is treating these serious biochemical illnesses.

·         Note: Liquid extracts act more effectively than tablets because they are absorbed directly into the blood stream and do not  go through the digestive tract where there is some loss. It takes at least two weeks to kick in. (This is typical as with other allopathic antidepressants )

 WHAT ARE ITS USES -PETS AND HORSES:

• May be used long term as part of a training regime for horses.

• Compulsive obsessive behaviour in dogs.

• Helpful in treating cats that urinate or spray indoors.

• For excessively nervous animals finding it hard to adjust to new surroundings

CAUTION:

Do not exceed the dose without consultation with a practitioner familiar with herbal products. Do not use in conjunction with other medication.

St John’s Wort must not be Taken in combination with allopathic antidepressants, HRT  or the contraceptive pill until the current research  on its possible effect as a liver flush on allopathic medicines has been fully completed.

Disclaimer: Information in this article is not to be used in place of professional medical advice and expertise. For diagnosis and treatment always see your health professional. We recommend that either a qualified herbalist or your animal professional carry out diagnosis and subsequent treatment. Herbal remedies must not be given not be taken in conjunction with other medication with out consulting a medical professional.